There is lots of news about CTE or chronic traumatic encephalopathy. CTE is a brain disease, a neurological degenerative disease that is caused by repetitive hits to the head. The symptoms include dementia, memory loss, and depression. In the early twentieth century, this condition was called “punch-drunk” and was found in a number of boxers who ultimately were found to suffer from dementia. No cure for CTE is currently known, and at present it can only be identified postmortem.

Here is an excerpt from Newtons Football (Affiliate Link), which describes where doctors are:

In the field of head injuries, scientists have a lot to try to understand as they parse the puzzle of concussions and the related long-term degenerative brain disease known as chronic traumatic encephalopathy, or CTE.
Just how does a concussive impact impair the function of the brain?

“You’ve got this metabolic crisis going on within the cell,” posits Robert Cantu, a professor of neurology at Boston University, as potassium ions flood out of the nerve cell, replaced by calcium ions, which prevent the cell from passing on information.”

Is there a genetic component to concussions and CTE?

“No one knows yet, but studies are focused on a variant of a common lipid transport gene called ApoE-e4. This gene does good things making sure fat goes to the right place,” says Robert Stern, a professor of neurology at Boston University, “but if you have the wrong form it does something crazy in the brain.” He adds that “it is a susceptibility gene, as opposed to a deterministic gene. If you have the wrong form, it increases your risk of having the disease, but it does not mean you will get it,” Stern explains. “There is not going to be a CTE gene because it is such a multifaceted disease.”

 

Newtons Football (Affiliate Link)

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